Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutchs pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer with minimal side effects. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nations first and largest cancer prevention research program, as well as the clinical coordinating center of the Womens Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.
The position focuses on the development, optimization, and transfer of cellular and gene therapy unit operations including cell selections from starting materials, genetic modifications (viral transduction, electroporation, etc.), growth/expansion conditions, media/cytokine formulations, cell harvests, cryopreservation, and freeze-thaw recovery. In addition, this position collaborates to develop robust and repeatable analytical methods to characterize starting, in-process, and final formulated cellular products. Ultimately, team development activities generate robust, repeatable and scalable processes to support toxicology studies, technology transfer/product introduction into the Fred Hutch GMP Cell Processing manufacturing facility, and IND generation to enable clinical trial initiation.
The Research Technician acts both independently and as a team collaborator to isolate, enrich, transduce, and expand T cells/Stem Cells. Execution of complex analytical procedures, along with data compilation, interpretation, and generation of detailed technical reports and presentations will be required. This position works with and under the guidance of a lab supervisor for experimental design, study execution, data analysis and data interpretation. The candidate will interact heavily with internal and external research and principal investigator labs, GMP manufacturing, Quality Control, Quality Assurance, and other scientific/administrative staff, as needed.
Research Tech I: Bachelors degree in a biological sciences discipline, and 1+ years' experience in mammalian cell culture
Research Tech II: BS/MS in a biological sciences discipline, and 2+ years' (BS) or 1+ years' (MS) experience in mammalian cell culture
Experience in one or more of the following technical areas:
Experience with gene editing platforms (i.e. Crispr/cas9 system)
Fed-batch, perfusion, disposable bioreactor systems
Cell culture media development and optimization
Cell banking, virus removal, purification, etc.
Cryopreservation and recovery of cryopreserved cells.
1+ years hands-on experience with flow cytometry and T-cell/stem cell isolation/expansion protocols
Direct experience supporting aseptic cell culture-based manufacturing operations
Experience in GMP manufacturing
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We are proud to be an Equal Employment Opportunity (EEO) and Vietnam Era Veterans Readjustment Assistance Act (VEVRAA) Employer. We are committed to cultivating a workplace in which diverse perspectives and experiences are welcomed and respected. We do not discriminate on the basis of race, color, religion, creed, ancestry, national origin, sex, age, disability (physical or mental), marital or veteran status, genetic information, sexual orientation, gender identity, political ideology, or membership in any other legally protected class. We are an Affirmative Action employer. We encourage individuals with diverse backgrounds to apply and desire priority referrals of protected veterans. If due to a disability you need assistance/and or a reasonable accommodation during the application or recruiting process, please send a request to our Employee Services Center at firstname.lastname@example.org or by calling 206-667-4700.
At Fred Hutchinson Cancer Research Center, teams of world-renowned scientists and humanitarians work together to prevent, diagnose and treat cancer, HIV/AIDS and other diseases. Researchers are discovering new ways to detect cancers earlier, improve treatments, and learn how to prevent cancers from growing. Although Fred Hutchinson opened its doors in 1975, its history began about 20 years before that. In 1962 Fred Hutchinson envisioned a center devoted to studying cancer, a disease that took his brother’s life. Today Fred Hutchinson is contributing to the next waves of breakthrough treatments and prevention strategies. Fred Hutchinson collaborates with the Seattle Cancer Alliance, the National Cancer Institute, and the University of Washington.